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DNA Signaling

Meaning

DNA Signaling refers to the intricate, highly regulated process by which external and internal cues influence gene expression, dictating the production of proteins and, consequently, cellular function. This molecular communication pathway is fundamental to endocrinology, as hormones themselves act as signaling molecules that directly interact with nuclear receptors to modulate DNA transcription. Effective DNA signaling is essential for all physiological processes, including metabolic adaptation, immune response, and the precise timing of hormonal cycles. Understanding and optimizing this signaling is key to promoting longevity and mitigating age-related functional decline.