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DNA Methylation Status

Meaning

DNA Methylation Status refers to the pattern of methyl groups covalently attached to cytosine bases in the DNA molecule, a fundamental epigenetic modification that profoundly influences gene expression without altering the underlying genetic code. This status functions as a dynamic cellular memory, accurately reflecting the cumulative impact of age, environmental exposures, and lifestyle on the genome’s functional output. Clinically, analyzing this specific pattern allows for the calculation of biological age and the precise assessment of long-term disease risk.