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DNA Methylation Sleep Deprivation

Meaning

DNA Methylation Sleep Deprivation refers to the measurable epigenetic changes in DNA methylation patterns that occur in response to insufficient or disrupted sleep. This clinical term highlights how sleep debt acts as an environmental stressor capable of altering gene expression without changing the underlying DNA sequence. These epigenetic modifications can affect genes involved in metabolism, inflammation, and stress response, demonstrating a tangible molecular link between sleep health and long-term physiological function. The resultant changes in gene activity can influence disease risk and accelerate biological aging.