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Diurnal Variation Management

Meaning

Diurnal variation management is the clinical strategy of acknowledging and proactively adjusting for the natural, predictable fluctuations in physiological parameters and key hormonal levels that occur over a 24-hour day. This sophisticated approach moves beyond single-point measurements to assess the dynamic range and timing of biomarkers like cortisol, glucose, and growth hormone. Effective management capitalizes on these inherent rhythms for optimal health outcomes and therapeutic efficacy.