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Diurnal Cortisol

Meaning

Diurnal Cortisol refers to the total circulating concentration of the body’s primary glucocorticoid hormone, cortisol, measured across the full 24-hour cycle. Cortisol, synthesized in the adrenal cortex, is integral to the stress response, glucose metabolism, and immune modulation. Clinically, evaluating its cumulative daily level provides crucial insight into the functional capacity and overall secretory output of the adrenal glands.