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Dipeptidyl Peptidase

Meaning

Dipeptidyl peptidase is a class of exopeptidase enzymes that function by cleaving a dipeptide, a sequence of two amino acids, from the N-terminus of a polypeptide chain. This enzymatic activity is a critical regulatory step in the metabolism and inactivation of numerous bioactive peptides throughout the body. In the context of hormonal health, the most significant isoform is Dipeptidyl Peptidase-4, or DPP-4, which directly influences glucose homeostasis.