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Diindylmethane (DIM)

Meaning

Diindolylmethane, commonly abbreviated as DIM, is a biologically active indole compound formed in the body upon the breakdown of indole-3-carbinol (I3C), a phytochemical abundant in cruciferous vegetables like broccoli and cabbage. It is recognized for its capacity to modulate estrogen metabolism by influencing the activity of cytochrome P450 enzymes in the liver. This action promotes a more favorable balance of estrogen metabolites, shifting the metabolic profile toward less proliferative forms.