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Diindolylmethane (DIM)

Meaning

Diindolylmethane, commonly referred to by its acronym DIM, is a naturally occurring compound formed in the stomach during the digestion of indole-3-carbinol, a phytonutrient found abundantly in cruciferous vegetables like broccoli, cabbage, and cauliflower. Clinically, DIM is recognized for its ability to beneficially modulate estrogen metabolism, promoting the formation of more favorable estrogen metabolites, such as 2-hydroxyestrone, over potentially less desirable ones, like 16-alpha-hydroxyestrone. It is frequently utilized in hormonal wellness protocols to support healthy estrogen balance and detoxification.