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Dihydrotestosterone Pathways

Meaning

Dihydrotestosterone Pathways delineate the specific metabolic routes and downstream actions of Dihydrotestosterone (DHT), a potent androgen derived from testosterone via the 5-alpha reductase enzyme. DHT is a critical mediator of male sexual differentiation and development of secondary sexual characteristics, possessing a significantly higher affinity for the androgen receptor than testosterone itself. Understanding these pathways is essential in hormonal health for managing conditions related to androgen excess, such as androgenic alopecia and benign prostatic hyperplasia, as well as optimizing the therapeutic benefits of testosterone replacement.