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Dihydrotestosterone Inhibition

Meaning

Dihydrotestosterone Inhibition is the pharmacological or physiological process specifically aimed at reducing the concentration or mitigating the potent biological activity of the androgen Dihydrotestosterone (DHT) within various target tissues. This inhibition is most commonly achieved by blocking the enzymatic action of 5-alpha reductase, which is the enzyme responsible for catalyzing the conversion of testosterone into the more potent DHT, thereby lessening the hormone’s effects on the hair follicles and prostate tissue. Clinical strategies employing this inhibition are widely used to manage conditions such as androgenetic alopecia and benign prostatic hyperplasia.