Dihexa Neurogenesis describes the process of stimulating the formation of new neurons and synapses within the central nervous system, specifically through the action of the small peptide Dihexa. This compound acts as a potent modulator of neurotrophic factors, aiming to enhance cognitive function, memory consolidation, and neural repair. It represents a targeted pharmacological approach to improving brain plasticity and health.
Origin
Dihexa is a derivative of a naturally occurring neuropeptide, Angiotensin IV, developed through research focused on enhancing the brain’s intrinsic regenerative capabilities. Its clinical application emerged from studies investigating treatments for neurodegenerative conditions and age-related cognitive decline. The term links the specific compound to the biological process it is designed to facilitate.
Mechanism
Dihexa functions by binding to and activating the Hepatocyte Growth Factor (HGF) receptor, also known as c-Met, which is critical for synaptogenesis and neuronal survival. This activation pathway dramatically amplifies the effects of HGF, leading to enhanced signaling cascades that promote the differentiation and proliferation of neural stem cells. The result is a measurable increase in neurogenesis and improved synaptic density in key brain regions.
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