Refers to the observed or hypothesized positive physiological effects of the peptide Dihexa, which is a potent, orally active analogue of Angiotensin IV. Its primary benefits are studied in the context of neurogenesis and synaptogenesis, suggesting potential for enhanced cognitive function, improved memory recall, and neuroprotective properties against age-related decline. These effects position it as a compound of interest in cognitive longevity.
Origin
Dihexa was developed through research on the Renin-Angiotensin System (RAS) and its non-pressor actions within the central nervous system, specifically targeting the Hepatocyte Growth Factor (HGF) receptor. Its development marks an advancement in peptide-based neuroscience and drug design. The original research aimed to isolate non-cardiovascular effects of RAS components.
Mechanism
The peptide functions by binding with high affinity to the HGF receptor (c-Met), acting as a strong agonist which stimulates the production of brain-derived neurotrophic factor (BDNF). This crucial signaling cascade promotes the formation of new synapses and strengthens existing neural connections. The overall effect directly supports neuroplasticity and overall brain health.
We use cookies to personalize content and marketing, and to analyze our traffic. This helps us maintain the quality of our free resources. manage your preferences below.
Detailed Cookie Preferences
This helps support our free resources through personalized marketing efforts and promotions.
Analytics cookies help us understand how visitors interact with our website, improving user experience and website performance.
Personalization cookies enable us to customize the content and features of our site based on your interactions, offering a more tailored experience.