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DHEA Sulfate Profiling

Meaning

DHEA Sulfate Profiling is a clinical assessment technique involving the precise measurement of dehydroepiandrosterone sulfate (DHEA-S) concentration in biological fluids, typically serum or saliva, often across multiple time points. This diagnostic approach provides a robust indicator of adrenal gland function, as DHEA-S is the most abundant circulating adrenal steroid. Profiling helps clinicians evaluate the reserve capacity of the adrenals and identify potential imbalances in the steroidogenesis pathway, which are often correlated with vitality, immune function, and stress adaptation.