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DHEA-S Replacement

Meaning

DHEA-S Replacement is a clinical strategy involving the therapeutic administration of dehydroepiandrosterone sulfate (DHEA-S) or its precursor, DHEA, to restore circulating levels to a youthful or optimal physiological range. This intervention is often considered for individuals exhibiting age-related decline or adrenal insufficiency, aiming to improve vitality, bone density, immune function, and overall hormonal balance. Because DHEA-S serves as a precursor to both androgens and estrogens, its replacement must be carefully monitored to prevent unintended downstream hormonal imbalances.