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DHEA-S Biomarker

Meaning

The DHEA-S Biomarker refers to Dehydroepiandrosterone sulfate, a steroid hormone metabolite measured in serum or saliva that serves as a crucial indicator of adrenal gland function and overall endocrine reserve. As the most abundant circulating steroid, its concentration reflects the cumulative secretory activity of the adrenal cortex, largely independent of acute daily stress fluctuations due to its long half-life. Clinically, DHEA-S levels are utilized to assess adrenal health, track aging-related decline, and evaluate the precursor pool for sex hormone synthesis. A stable DHEA-S level often correlates with resilience and metabolic vitality.