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DHEA Prohormone Risks

Meaning

DHEA Prohormone Risks refer to the potential adverse outcomes and clinical liabilities associated with the exogenous administration of Dehydroepiandrosterone (DHEA), a steroid prohormone naturally produced by the adrenal glands. As DHEA is a precursor to both androgens and estrogens, its supplementation carries the inherent risk of unintended or excessive peripheral conversion to these downstream, potent sex hormones. These risks include dermatological side effects, such as acne and hirsutism, potential strain on the liver, and the significant possibility of disrupting the body’s native, tightly regulated endocrine feedback loops.