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DHEA Elevation

Meaning

DHEA Elevation refers to a clinically measured state where the circulating concentration of Dehydroepiandrosterone (DHEA) or its sulfated form, DHEA-S, is significantly above the established reference range for an individual’s age and sex. DHEA is a primary adrenal androgen precursor, a steroid hormone synthesized primarily by the adrenal glands and, to a lesser extent, by the gonads. While often viewed positively in the context of age-related decline, pathologically high levels can indicate underlying endocrine disorders, such as adrenal hyperplasia or certain adrenal tumors, requiring careful differential diagnosis. This hormonal state warrants clinical investigation to determine its etiology and potential health implications.