What is the Origin of DHEA Adrenal Support?

This concept arose from the understanding of the adrenal cortex's central role in the stress response and the age-related decline of DHEA production, often termed the "adrenopause." Clinical endocrinologists recognized the potential for DHEA supplementation to support the HPA axis and counteract the catabolic effects of elevated cortisol, leading to the designation of adrenal support.

What is the Mechanism of DHEA Adrenal Support?

The mechanism is two-fold: DHEA directly supports the adrenal axis by serving as a negative feedback signal, which can modulate excessive ACTH release and help normalize cortisol rhythms. Simultaneously, DHEA is peripherally converted into potent androgens and estrogens, providing systemic benefits to muscle, bone, and brain tissue. This dual action helps restore a favorable anabolic-to-catabolic balance, thereby lessening the chronic burden on the adrenal glands.

DHEA Adrenal Support

Meaning

DHEA Adrenal Support is a clinical strategy involving the use of Dehydroepiandrosterone (DHEA) or its precursors to modulate and assist the function of the adrenal glands, particularly in states of chronic stress, adrenal fatigue, or age-related decline. DHEA, a primary adrenal androgen, acts as a precursor to other sex steroids and also possesses intrinsic anti-inflammatory and neuroprotective properties. Judicious supplementation aims to restore optimal adrenal reserve and systemic hormonal balance.