A forward-thinking, clinical concept asserting that human physiology is not merely a static consequence of genetics, but a dynamic system that can be intentionally and scientifically guided toward optimal function. This approach utilizes targeted interventions, informed by comprehensive biomarker data, to proactively enhance biological systems and resilience. It moves beyond passive acceptance of decline to active physiological optimization.
Origin
This term synthesizes principles from precision medicine, genomics, and systems biology, framing the body as a system whose performance can be ‘designed’ or engineered. It is a philosophical shift in clinical practice toward realizing maximal human potential. The evolution of genetic sequencing capabilities enabled this perspective.
Mechanism
The underlying mechanism involves leveraging the body’s inherent homeostatic and adaptive capabilities through precise input signals, such as nutraceuticals, lifestyle modification, and targeted hormonal support. This biological engineering aims to modulate gene expression, optimize mitochondrial function, and reinforce neuroendocrine feedback loops. The ultimate goal is to effectively override suboptimal genetic or environmental programming.
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