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Desensitization Avoidance Protocols

Meaning

Clinically applied strategies designed to prevent the progressive loss of cellular responsiveness to specific hormones, peptides, or pharmaceutical agents. These protocols are implemented to maintain the long-term efficacy of a therapeutic agent by preserving the sensitivity and concentration of its target receptors. The central goal is to circumvent the physiological adaptation where continuous stimulation leads to diminished biological effect. This requires careful consideration of dosing, timing, and cycling of therapeutic agents.