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Dermal Barrier Function

Meaning

Dermal barrier function refers to the primary protective capacity of the outermost layer of the skin, the stratum corneum, to maintain internal homeostasis and shield the body from external stressors. This essential function involves controlling Transepidermal Water Loss (TEWL) and preventing the penetration of irritants, allergens, and pathogens. A robust dermal barrier is fundamental to skin health, hydration, and resilience against environmental and inflammatory challenges.