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Delayed Gastric Emptying

Meaning

Delayed gastric emptying, also known as gastroparesis, is a physiological condition characterized by the slowed movement of food from the stomach into the small intestine. This deceleration disrupts the normal digestive timeline, leading to symptoms like early satiety, nausea, and bloating. In the hormonal context, this is a particularly relevant effect of certain incretin-mimetic drugs, such as GLP-1 agonists, which are clinically used to manage type 2 diabetes and obesity. The resulting prolonged food retention significantly impacts postprandial glucose control and enhances the sensation of fullness.