Skip to main content

De Novo Steroidogenesis

Meaning

De Novo Steroidogenesis describes the complete biological process of synthesizing steroid hormones from their fundamental precursor, cholesterol, within the steroidogenic tissues. The Latin phrase de novo translates to “from the beginning,” emphasizing that this pathway involves the creation of hormones entirely within the cell, rather than simply modifying or converting an existing steroid molecule. This is the primary method of hormone production in the adrenal glands, gonads, and placenta. Understanding this pathway is central to comprehending endocrine function.