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De-Immunization

Meaning

De-Immunization refers to a therapeutic strategy aimed at reducing or completely eliminating an undesirable immune response against a specific substance, often an administered hormone or protein-based drug. This intervention is necessary when a patient’s immune system recognizes the therapeutic agent as foreign, leading to the production of neutralizing antibodies that render the treatment ineffective or cause adverse reactions. The goal is to induce a state of immunological tolerance to the required medication. This clinical process is distinct from simple immunosuppression, aiming for a more specific, long-lasting change.