Daylight Exposure Dosing refers to the calculated prescription of daily exposure to natural light, calibrated by intensity and duration, to optimize endocrine function, particularly the regulation of the sleep-wake cycle. This is not merely about being outdoors; it is a precise intervention targeting the melanopsin receptors in the retina. Appropriate dosing is essential for anchoring the suprachiasmatic nucleus and ensuring robust nocturnal melatonin production. We view this as a non-pharmacological modulator of the neuroendocrine system.
Origin
This concept originates from the foundational principles of chronobiology and photobiology, recognizing light as a primary environmental synchronizer. ‘Dosing’ borrows terminology from pharmacology, implying a specific, therapeutic amount is required for a desired effect. It signifies a move from passive exposure to active management of light intake.
Mechanism
The mechanism involves specific wavelengths of light, primarily in the blue spectrum, activating intrinsically photosensitive retinal ganglion cells (ipRGCs). These cells signal the SCN, which in turn modulates the pineal gland’s output of melatonin, a key hormone. Correct morning dosing suppresses morning cortisol slightly while setting the stage for appropriate evening prolactin and melatonin release.
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