Skip to main content

Cytokine Cascade Management

Meaning

Cytokine cascade management is the clinical and therapeutic strategy focused on modulating the complex, sequential release and interaction of small protein signaling molecules, known as cytokines, that govern the body’s inflammatory and immune responses. The central goal is to prevent or mitigate an uncontrolled, self-amplifying inflammatory reaction, often termed a cytokine storm, which can lead to significant tissue damage and systemic dysfunction. Effective management aims to maintain a state of immune tolerance and low-grade, balanced inflammation necessary for tissue repair and defense. This balance is critical for preventing hormonal resistance.