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Cyclic Therapeutic Administration

Meaning

Cyclic Therapeutic Administration refers to the clinical practice of prescribing pharmaceutical or nutritional agents in a pattern that includes periods of administration followed by planned periods of cessation or a lower dose. This dosing schedule is deliberately designed to mimic natural physiological rhythms or to prevent receptor down-regulation and systemic adaptation. The strategy is commonly employed in hormone replacement therapy to simulate the body’s endogenous hormonal cycles, such as the menstrual cycle, or to maintain therapeutic efficacy over the long term. It is a precise approach that contrasts with continuous, steady-state dosing.