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CSMD1 Gene

Meaning

The CSMD1 gene, or CUB and Sushi Multiple Domains 1, encodes a very large protein that functions as a cell surface receptor and is thought to play a role in complement regulation, cell adhesion, and crucial neuronal development. While its primary physiological functions are diverse, specific single nucleotide polymorphisms (SNPs) within this gene have been clinically associated with various complex conditions, including susceptibility to certain cancers and neurodevelopmental disorders. In the broader context of health and longevity, its involvement in cell signaling pathways suggests an indirect but important role in systemic regulation, which is often influenced by the surrounding hormonal environment. Genetic variations in this gene are frequently studied in the field of personalized medicine.