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Cortisol-Testosterone Axis

Meaning

The Cortisol-Testosterone Axis describes the reciprocal relationship between cortisol, a primary stress hormone from the adrenal glands, and testosterone, a key androgen primarily synthesized in the gonads. Elevated cortisol levels, often a response to physiological or psychological stressors, typically lead to a suppression of testosterone production and action. This endocrine interplay influences various physiological functions.