The clinical strategy of utilizing targeted physical activity to mitigate or reduce chronically elevated baseline cortisol levels, thereby promoting a healthier hormonal milieu. While acute, intense exercise temporarily raises cortisol, the long-term, adaptive effect of consistent, appropriately dosed fitness is a reduction in HPA axis overactivity. This adaptation is crucial for stress resilience and metabolic health.
Origin
This concept merges the understanding of endocrinology, specifically HPA axis regulation, with exercise physiology. The term “suppression” in this context refers to normalization of pathological hypercortisolemia, not complete cessation of the hormone’s vital functions. Its application is rooted in clinical practice observing the stress-buffering effects of structured physical training.
Mechanism
Regular physical fitness enhances the sensitivity of the glucocorticoid receptors, allowing the body to respond more efficiently to lower circulating cortisol levels. Furthermore, consistent exercise can improve parasympathetic tone and modulate the hypothalamic drive for CRH release, effectively dampening the chronic stress response. This neuroendocrine adaptation fosters a more balanced hormonal state, minimizing catabolic effects.
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