Skip to main content

Cortisol Rhythm Regulation

Meaning

Cortisol rhythm regulation is the clinical effort to restore the natural, diurnal pattern of cortisol secretion, which is crucial for managing stress, energy levels, and inflammatory responses. Cortisol, a glucocorticoid hormone, should naturally peak in the morning to promote wakefulness and gradually decline throughout the day, reaching its lowest point near midnight. Disruption of this circadian rhythm, often due to chronic stress or HPA axis dysfunction, can negatively impact sleep, metabolism, and immune function. Therapeutic regulation aims to re-establish this healthy, pulsatile release pattern.