Skip to main content

Cortisol Rhythm

Meaning

The Cortisol Rhythm, often referred to as the Cortisol Awakening Response or the diurnal cortisol cycle, describes the predictable, cyclical pattern of the glucocorticoid hormone cortisol secretion over a 24-hour period. This rhythm is a key output of the hypothalamic-pituitary-adrenal (HPA) axis, reflecting the body’s precise orchestration of its stress response and wakefulness state. A healthy rhythm is characterized by a sharp rise shortly after waking, followed by a gradual decline throughout the day, reaching its nadir around midnight.