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Cortisol Resilience

Meaning

Cortisol Resilience refers to the body’s physiological capacity to maintain adaptive and appropriate HPA axis function despite chronic or acute stressors. It is the ability of the neuroendocrine system to efficiently regulate cortisol secretion, binding, and receptor sensitivity, preventing the detrimental effects of sustained dysregulation. A resilient system allows for a swift return to homeostatic balance following a stressor, preserving metabolic and immune integrity. This functional capacity is a key indicator of long-term stress adaptation.