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Cortisol Regulation Brain Health

Meaning

Cortisol Regulation Brain Health refers to the clinical focus on maintaining the appropriate circadian rhythm and overall systemic balance of the stress hormone cortisol to preserve optimal neurological and cognitive function. Chronic dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, leading to sustained high or abnormally low cortisol exposure, can exert neurotoxic effects, impairing hippocampal neurogenesis and prefrontal cortex function. Effective regulation is essential for mood stability, memory consolidation, and protecting the brain from stress-induced atrophy.