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Cortisol Recalibration

Meaning

Cortisol recalibration refers to the physiological process of restoring optimal regulation of cortisol secretion and cellular response within the body. This involves adjusting the activity of the Hypothalamic-Pituitary-Adrenal (HPA) axis, which governs the release of this critical stress hormone. The aim is to achieve a balanced diurnal rhythm and appropriate stress reactivity, moving away from states of chronic hyper- or hypo-cortisolism.