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Cortisol Metabolite Analysis

Meaning

Cortisol Metabolite Analysis is a specialized laboratory technique that quantifies the levels of both active cortisol and its downstream, inactivated metabolites, such as tetrahydrocortisol and tetrahydrocortisone, typically measured in urine or saliva. This comprehensive assessment provides a more accurate picture of total cortisol production and the efficiency of its clearance and inactivation pathways over a full 24-hour period. Clinical interpretation of these metabolites offers deeper insight into adrenal function and hepatic detoxification capacity than measuring serum cortisol alone.