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Cortisol Metabolism

Meaning

Cortisol Metabolism encompasses the entire physiological process of cortisol, the body’s primary glucocorticoid, beginning with its synthesis in the adrenal cortex and proceeding through its systemic circulation, deactivation, and final excretion. This complex biochemical pathway dictates the precise levels of active cortisol and its inactive metabolite, cortisone, in tissues, profoundly influencing the body’s essential stress response and glucose homeostasis. Understanding this complete metabolic process is paramount for accurately assessing adrenal function and overall systemic stress adaptation.