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Cortisol Load Mitigation

Meaning

Cortisol Load Mitigation is the precise clinical strategy focused on reducing the cumulative, potentially detrimental physiological impact of chronically elevated or severely dysregulated cortisol exposure on the body’s various tissues and systems. This therapeutic goal is not merely about lowering a single serum cortisol measurement but comprehensively addressing the total allostatic load imposed by the body’s primary stress hormone over time. Effective mitigation aims to restore the healthy, rhythmic diurnal variation of the hypothalamic-pituitary-adrenal (HPA) axis, thereby minimizing catabolism and preserving crucial immune and metabolic function.