What is the Origin of Cortisol Diurnal Rhythm Mapping?

The methodology originates directly from chronobiology and clinical endocrinology, acknowledging that hormone secretion is not static but follows predictable circadian patterns necessary for health. This approach evolved to offer a more nuanced functional assessment compared to single-point serum cortisol measurements, which fail to capture the dynamic regulatory capacity. The timing of cortisol release is tightly controlled by the body's master clock.

What is the Mechanism of Cortisol Diurnal Rhythm Mapping?

The assessment relies on collecting samples at waking, midday, late afternoon, and before bed, to capture the dynamic release profile of cortisol, which is tightly regulated by the suprachiasmatic nucleus (SCN) of the hypothalamus. This functional data allows clinicians to identify specific phases of rhythm dysregulation, such as a failure in the Cortisol Awakening Response (CAR) or inappropriate evening hypersecretion, guiding targeted therapeutic intervention.

Cortisol Diurnal Rhythm Mapping ∞ Area

Cortisol Diurnal Rhythm Mapping

Meaning

Cortisol Diurnal Rhythm Mapping is a precise diagnostic technique used to measure and plot the concentration of the stress hormone cortisol at multiple specific time points throughout a 24-hour cycle. This mapping provides a critical visualization of the HPA axis function, revealing the essential pattern of high morning levels and low evening levels, which is crucial for optimal energy and sleep cycles. Deviations from this predictable rhythm, such as a flattened or inverted curve, are highly indicative of chronic stress or adrenal dysfunction.