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Cortisol Chronicity Reversal

Meaning

This is a therapeutic objective aimed at normalizing a pathologically flattened or excessively elevated diurnal cortisol curve that has resulted from prolonged, unmanaged chronic stress. It signifies the clinical process of restoring the healthy, pulsatile, and rhythmically appropriate secretion of cortisol from the adrenal glands. Achieving reversal is essential for mitigating the long-term, systemic inflammatory and metabolic damage associated with chronic HPA axis dysregulation. This restoration is a key step in reclaiming full metabolic and immune function.