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Cortisol Axis Management

Meaning

The clinical process of assessing, monitoring, and therapeutically modulating the activity of the Hypothalamic-Pituitary-Adrenal (HPA) axis, specifically focusing on the production and circulating levels of the glucocorticoid hormone, cortisol. Effective management is essential for maintaining systemic homeostasis, as dysregulation of this stress axis can negatively impact metabolic function, immune response, and sleep architecture. The goal is to ensure an appropriate, adaptive cortisol response without chronic hyper- or hypo-secretion.