Cortisol Awakening Response Assessment (CAR Assessment) is a specific clinical procedure used to evaluate the acute, predictable surge of cortisol that occurs within 30 to 45 minutes after waking. This response serves as a sensitive biomarker reflecting the functional status and reactivity of the HPA axis to anticipated daily demands. Analyzing the magnitude and shape of this initial spike provides crucial insight into underlying stress resilience. It is a dynamic snapshot of the body’s morning readiness.
Origin
The CAR itself is a well-established phenomenon in endocrinology, initially studied to understand feedback sensitivity independent of acute external stressors. Assessment protocols were formalized to standardize measurement, often utilizing salivary sampling collected at defined intervals post-awakening. The term highlights the focus on quantifying this specific, non-stress-induced hormonal event. It directly links to the body’s intrinsic preparation for the day.
Mechanism
The assessment mechanism involves measuring the increase in free, unbound cortisol concentration across the initial post-waking window. A robust, yet controlled, rise indicates healthy HPA axis feedback sensitivity and adequate morning energy mobilization potential. Conversely, a blunted or excessively high response suggests underlying issues in pituitary signaling or adrenal habituation. Interpretation guides interventions aimed at normalizing the morning neuroendocrine activation profile.
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