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Cortisol Antagonism

Meaning

Cortisol antagonism describes the clinical or pharmacological action of blocking or reducing the biological effects of the stress hormone cortisol at its receptor sites or by interfering with its synthesis. This intervention is often employed to mitigate the catabolic and immunosuppressive consequences of chronic or excessive cortisol exposure. Effective antagonism helps restore a favorable anabolic-to-catabolic balance within the body.