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Cortisol and Edema

Meaning

Cortisol and Edema refers to the established clinical link between the stress hormone cortisol and the pathological accumulation of interstitial fluid, known as edema. Elevated or dysregulated cortisol levels can directly contribute to fluid retention by affecting the body’s electrolyte and water balance. This relationship is a key consideration in endocrinology, particularly when evaluating patients with unexplained swelling or known adrenal gland dysfunction. Recognizing this hormonal etiology is essential for effective clinical management.