What is the Origin of CoQ10?

The term is an abbreviation for Coenzyme Q10, where "Coenzyme" denotes its role as a necessary partner for enzyme function, and "Q10" refers to its chemical structure with a quinone head and a ten-unit isoprenoid tail. It was first identified in 1957, and its fundamental role in cellular energy metabolism was quickly established.

What is the Mechanism of CoQ10?

Within the inner mitochondrial membrane, CoQ10 accepts electrons from complexes I and II and transfers them to complex III, facilitating the proton gradient necessary for ATP synthesis via oxidative phosphorylation. Beyond energy production, its antioxidant function involves neutralizing reactive oxygen species within the mitochondrial membrane, thereby protecting lipids and proteins from oxidative damage. The body's endogenous synthesis of CoQ10 declines with age and can be inhibited by certain medications.

CoQ10

Meaning

Coenzyme Q10, a fat-soluble benzoquinone that functions as a critical component in the mitochondrial electron transport chain and serves as a potent endogenous antioxidant. This essential compound is vital for the production of adenosine triphosphate (ATP), the primary energy currency of the cell, making it indispensable for the function of high-energy demand organs such as the heart, brain, and endocrine glands. It exists in two forms: ubiquinone and the reduced, active form, ubiquinol.