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Continuous Combined Regimen

Meaning

A continuous combined regimen is a specific, standardized dosing protocol utilized in Hormone Replacement Therapy (HRT), typically for postmenopausal women, that involves the daily, uninterrupted administration of both an estrogen and a progestogen compound. The central clinical purpose of this regimen is to provide consistent relief from menopausal symptoms while concurrently preventing the estrogen-driven overgrowth of the uterine lining. This method is designed to achieve a state of endometrial quiescence, which generally results in the absence of monthly withdrawal bleeding.