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Connective Tissue Signaling

Meaning

The complex biochemical communication network originating from and within the connective tissues, such as bone, cartilage, tendons, and the extracellular matrix. This signaling involves the release of specific molecules, including growth factors, cytokines, and matrix metalloproteinases, which influence tissue remodeling, repair, and the structural integrity of the body. It is a critical component of mechanotransduction, translating physical forces into biochemical responses that impact systemic health.