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Connective Tissue Repair Signaling

Meaning

The complex cascade of biochemical communication pathways initiated in response to damage or stress within tissues like tendons, ligaments, cartilage, and skin, with the primary objective of restoring structural integrity and function. This signaling network involves the coordinated release of growth factors, cytokines, and matrix metalloproteinases to regulate fibroblast, chondrocyte, and osteoblast activity. Optimal hormonal balance is crucial for maintaining the vigor of this repair system, influencing both the speed and quality of tissue regeneration.