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Conjugated Peptides

Meaning

Conjugated peptides are therapeutic peptide molecules that have been chemically linked to another non-peptide molecule, known as a conjugate, to enhance their pharmacological properties. The conjugate can be a lipid, a fatty acid chain, polyethylene glycol (PEG), or a protein like albumin, all strategically chosen for their biological effects. This chemical modification is primarily executed to improve the peptide’s stability, increase its half-life in the bloodstream, and optimize its delivery to target tissues. Conjugation is a critical strategy in endocrinology to transform short-acting natural hormones or growth factors into clinically viable, long-acting drug formulations.