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Concentration Capacity

Meaning

Concentration Capacity, in the context of hormonal health, refers to the physiological limit or maximum ability of a target tissue or organ system to effectively respond to and utilize a signaling molecule. It is not simply the amount of hormone present but the tissue’s intrinsic ability to process that signal, often limited by the number of available receptors or the saturation point of downstream enzymes. Once this capacity is reached, further increases in systemic hormone concentration yield no additional biological benefit and may even increase the risk of side effects. This principle is vital for establishing clinically meaningful upper dosing limits.